Effects of Aluminium Chloride Exposure on the Histology of the Small intestine of Wistar Rats

The small intestine is the largest component of the digestive tract and the major site of digestion and absorption. Aluminium compounds are used in pharmaceuticals and in water treatment processes. The purpose of this experiment was to evaluate the possible effects that aluminium chloride exposure could have on the histology of the small intestine of wistar rats. The wistar rats were divided into five groups as follows: Group I was the control that received distil water only while Groups II-V were given various concentrations of aluminium chloride via oral intubation for period of eight weeks. The wistar rats were humanely sacrificed, the small intestine removed, fixed, processed and stained in haematoxylin and eosin (H&E).The slides were viewed under the light microscope fitted to a digital camera. Based on our observations, we therefore conclude that aluminium chloride exposure had negative and deleterious effects on the histology of small intestine of wistar rats as eminent in mucosa degeneration.